RON Rabbit monoclonal antibody
Product Specifications
Background
Ron is initially synthesized in the cells as a single-chain, pro-Ron precursor that is cleaved into the two active chains. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
C met related tyrosine kinase; CD136 antigen; Macrophage stimulating 1 receptor; MSP receptor; p185 RON; PTK 8 Stem cell derived tyrosine kinase; MST1R variant RON30; MST1R variant RON62
Swiss Prot
Q04912
Reactivity
Human
Immunogen
A synthesized peptide derived from human RON
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP FC
Dilution
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:30
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
185kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RON Antibody detects endogenous levels of RON
Applications Notes
Western blot analysis of RON expression in SKBR3 cell lysate.
Host or Source
Rabbit
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