Phospho-BTK (Y551) Rabbit monoclonal antibody
Product Specifications
Background
Bruton's tyrosine kinase (Btk) is a member of the Btk/Tec family of cytoplasmic tyrosine kinases. Like other Btk family members, it contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. Btk plays an important role in B cell development. Activation of B cells by various ligands is accompanied by Btk membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
BTK, AGMX1, AT, ATK, XLA, PSCTK1, B-cell progenitor kinase, BPK, Bruton tyrosine kinase, Tyrosine-protein kinase BTK, IMD1
Swiss Prot
Q06187
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-BTK (Y551)
Conjugation
Unconjugated
Applications
WB ICC/IF
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
74kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-BTK (Y551) Antibody detects endogenous levels of Phospho-BTK (Y551)
Applications Notes
Western blot analysis of Phospho-BTK (Y551) expression in Ramos cell lysate treated with Pervanadate.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH031639 100 µg
Recombinant Human TNFSF14/LIGHT Protein (His Tag)
Sign In for Pricing
View Details 
TRC-H939700-1MG 1 mg
1-Hydroxy-2,7-diamino Mitosene (Mixture cis/trans)
Sign In for Pricing
View Details