Phospho-BTK (Y551) Rabbit monoclonal antibody
Product Specifications
Background
Bruton's tyrosine kinase (Btk) is a member of the Btk/Tec family of cytoplasmic tyrosine kinases. Like other Btk family members, it contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. Btk plays an important role in B cell development. Activation of B cells by various ligands is accompanied by Btk membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
BTK, AGMX1, AT, ATK, XLA, PSCTK1, B-cell progenitor kinase, BPK, Bruton tyrosine kinase, Tyrosine-protein kinase BTK, IMD1
Swiss Prot
Q06187
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-BTK (Y551)
Conjugation
Unconjugated
Applications
WB ICC/IF
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
74kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-BTK (Y551) Antibody detects endogenous levels of Phospho-BTK (Y551)
Applications Notes
Western blot analysis of Phospho-BTK (Y551) expression in Ramos cell lysate treated with Pervanadate.
Host or Source
Rabbit
Available Sizes
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