Phospho-SIRT1 (S47) Rabbit monoclonal antibody

Product Specifications

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

HSIR2; hSIRT1; NAD-dependent deacetylase sirtuin 1; SIR1; SIR2-like protein 1

Swiss Prot

Q96EB6

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-SIRT1 (S47)

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

110kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-SIRT1 (S47) Antibody detects endogenous levels of Phospho-SIRT1 (S47)

Applications Notes

Western blot analysis of Phospho-SIRT1 (S47) expression in (1) HEK293 cell lysate; (2) HEK293 cell lysate treated with LP.

Host or Source

Rabbit

Available Sizes

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