SGK1 Rabbit monoclonal antibody
Product Specifications
Background
Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
EC 2.7.11.1; SGK; SGK1; Serum/glucocorticoid-regulated kinase; Sgk; Sgk1; kinase SGK
Swiss Prot
O00141
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human SGK1
Conjugation
Unconjugated
Applications
WB IHC IP FC
Dilution
WB 1:500~1:1000 IHC 1:50~1:200 IP 1:50 FC 1:30
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
57kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SGK1 Antibody detects endogenous levels of SGK1
Applications Notes
Western blot analysis of SGK1 expression in A431 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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