PP2A alpha + beta Rabbit monoclonal antibody
Product Specifications
Background
Protein phosphatase type 2A (PP2A) is an essential protein serine/threonine phosphatase that is conserved in all eukaryotes. PP2A is a key enzyme within various signal transduction pathways as it regulates fundamental cellular activities such as DNA replication, transcription, translation, metabolism, cell cycle progression, cell division, apoptosis and development. The core enzyme consists of catalytic C and regulatory A (or PR65) subunits, with each subunit represented by α and β isoforms.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
PP2A alpha; PP2A beta; Replication protein C; PPP2CA; PPP2CB
Swiss Prot
P62714/P67775
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human alpha + beta PP2A
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
~ 35 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PP2A alpha + beta Antibodydetects endogenous levels of total PP2A alpha + beta
Applications Notes
Western blot (WB) analysis of PP2A alpha + beta Rabbit monoclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (30ug) Lane2:HEK293T whole cell lysate (30ug) Lane3:The Liver tissue lysate of Mouse (30ug) Lane4:The Brain tissue lysate of Rat (30ug)
Host or Source
Rabbit
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