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PP2A alpha + beta Rabbit monoclonal antibody

Product Specifications

Background

Protein phosphatase type 2A (PP2A) is an essential protein serine/threonine phosphatase that is conserved in all eukaryotes. PP2A is a key enzyme within various signal transduction pathways as it regulates fundamental cellular activities such as DNA replication, transcription, translation, metabolism, cell cycle progression, cell division, apoptosis and development. The core enzyme consists of catalytic C and regulatory A (or PR65) subunits, with each subunit represented by α and β isoforms.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

PP2A alpha; PP2A beta; Replication protein C; PPP2CA; PPP2CB

Swiss Prot

P62714/P67775

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human alpha + beta PP2A

Conjugation

Unconjugated

Applications

WB IHC ICC/IF IP

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

~ 35 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PP2A alpha + beta Antibodydetects endogenous levels of total PP2A alpha + beta

Applications Notes

Western blot (WB) analysis of PP2A alpha + beta Rabbit monoclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (30ug) Lane2:HEK293T whole cell lysate (30ug) Lane3:The Liver tissue lysate of Mouse (30ug) Lane4:The Brain tissue lysate of Rat (30ug)

Host or Source

Rabbit

Available Sizes

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