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Phospho-BTK (Y223) Rabbit monoclonal antibody

Product Specifications

Background

Defects in the Bruton tyrosine kinase (BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Agammaglobulinaemia tyrosine kinase; AGMX1; ATK; B cell progenitor kinase; BPK; Bruton's tyrosine kinase; EC 2.7.10.2; kinase Btk; Kinase EMB

Swiss Prot

Q06187

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-BTK (Y223)

Conjugation

Unconjugated

Applications

WB IP

Dilution

WB 1:1000~1:2000 IP 1:20

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

76kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-BTK (Y223) Antibody detects endogenous levels of total Phospho-BTK (Y223)

Applications Notes

Western blot analysis of Phospho-BTK (Y223) expression in Raji cell lysate treated with pervanadate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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