Lin28B Rabbit monoclonal antibody
Product Specifications
Background
It has recently been shown that upregulation of LIN28A and LIN28B in primary human tumors and human cancer cell lines is correlated with downregulation of let-7 miRNAs. LIN28 genes are reported to be involved in primordial germ cell development and germ cell malignancy. In addition, allelic variation in LIN28B is associated with regulating the timing of puberty in humans.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B
Swiss Prot
Q6ZN17
Reactivity
Human
Immunogen
A synthesized peptide derived from human Lin28B
Conjugation
Unconjugated
Applications
WB ICC/IF IP FC
Dilution
WB 1:500~1:2000 ICC/IF 1:100~1:500 IP 1:50 FC 1:100
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
30kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Lin28B Antibody detects endogenous levels of total Lin28B
Applications Notes
Western blot analysis of Lin28B expression in K562 cell lysate.
Host or Source
Rabbit
Available Sizes
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