RPS3 Rabbit monoclonal antibody
Product Specifications
Background
Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) . Has also been shown to bind with similar affinity to intact and damaged DNA.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
RPS3; 40S ribosomal protein S3
Swiss Prot
P23396
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human RPS3
Conjugation
Unconjugated
Applications
WB IHC ICC/IF
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
27kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RPS3 Antibody detects endogenous levels of total RPS3
Applications Notes
Western blot analysis of RPS3 expression in HepG2 cell lysate.
Host or Source
Rabbit
Available Sizes
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