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C-Maf Rabbit monoclonal antibody

Product Specifications

Background

Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene; c-MAF; c-maf proto-oncogene; cMaf; MAF; MGC71685; Proto-oncogene c-Maf

Swiss Prot

O75444

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human c-Maf

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

KDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

C-Maf Antibody detects endogenous levels of total c-Maf

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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