C-Maf Rabbit monoclonal antibody
Product Specifications
Background
Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene; c-MAF; c-maf proto-oncogene; cMaf; MAF; MGC71685; Proto-oncogene c-Maf
Swiss Prot
O75444
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human c-Maf
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
C-Maf Antibody detects endogenous levels of total c-Maf
Host or Source
Rabbit
Available Sizes
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