Caspase-2 Rabbit monoclonal antibody
Product Specifications
Background
Caspase-2 (Nedd2, ICH-1) is an aspartate-specific cysteine protease that is activated in response to various apoptotic stimuli. Caspase-2 is unique among the caspases in that it has features of both upstream caspases (long prodomain) and downstream caspases (DEXD substrate specificity) . Caspase-2 is highly expressed in the brain during development and is expressed at low levels in adult tissue.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Caspase-2; Caspase 2; Caspase2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; CASP2; ICH1; NEDD2
Swiss Prot
P42575
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human Caspase-2
Conjugation
Unconjugated
Applications
WB IHC ICC/IF FC
Dilution
WB 1:500~2000 IHC 50~200 ICC/IF 50~200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
48,30,12kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Caspase-2 Antibody detects endogenous levels of total Caspase-2
Applications Notes
Western blot analysis of Caspase-2 expression in Jurkat cell lysate.
Host or Source
Rabbit
Available Sizes
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