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Myosin light chain kinase Rabbit monoclonal antibody

Product Specifications

Background

Regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

KMLS; KRP; MLCK; MYLK; myosin light chain kinase, smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin

Swiss Prot

Q15746

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human Myosin light chain kinase

Conjugation

Unconjugated

Applications

WB IHC ICC/IF FC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

200kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Myosin light chain kinase Antibody detects endogenous levels of total Myosin light chain kinase

Applications Notes

Western blot analysis of myosin light chain kinase expression in HUVEC cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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