CD86 Rabbit monoclonal antibody
Product Specifications
Background
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CD86; B7-2; B70; CD28LG2; LAB72; MGC34413; CTLA4 counter receptor B72; CLS1; Ly58; MB7
Swiss Prot
P42081
Reactivity
Human Rat
Immunogen
A synthesized peptide derived from human CD86
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP FC
Dilution
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD86 Antibody detects endogenous levels of total CD86
Applications Notes
Western blot (WB) analysis of CD86 Rabbit monoclonal antibody at 1:500 dilution Lane1:Raji whole cell lysate (30ug) Lane2:HuT78 whole cell lysate (30ug) Lane3:The Lung tissue lysate of Mouse (30ug) Lane4:CT-26 whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
Curated Selection
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