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HIF-1 alpha Rabbit monoclonal antibody

Product Specifications

Background

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT) . This gene encodes the alpha subunit of HIF-1.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF1A

Swiss Prot

Q16665

Reactivity

Human

Immunogen

A synthesized peptide derived from human HIF-1 alpha

Conjugation

Unconjugated

Applications

WB IHC ICC/IF IP FC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:30

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

120kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

HIF-1 alpha Antibody detects endogenous levels of total HIF-1 alpha

Applications Notes

Western blot analysis of HIF-1 alpha expression in Ramos cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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