Phospho-alpha Synuclein (S129) Rabbit monoclonal antibody
Product Specifications
Background
SNCA a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson's disease. A major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced isoforms transcripts have been identified.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Alpha-synuclein; NACP; non A-beta component of AD amyloid; PARK1; PARK4; PD1; SNCA
Swiss Prot
P37840
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-alpha Synuclein (S129)
Conjugation
Unconjugated
Applications
WB IHC ICC/IF
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Phosphorylated
Molecular Weight
18kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-alpha Synuclein (S129) Antibody detects endogenous levels of total Phospho-alpha Synuclein (S129)
Applications Notes
Western blot analysis of Phospho-alpha Synuclein (Ser129) expression in (1) 293T cell lysate; (2) 293T cell lysate transfected with Polo-Like Kinase 2 and alpha Synuclein.
Host or Source
Rabbit
Available Sizes
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