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Histone H3 (acetyl K56) Rabbit monoclonal antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

H3/a; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H31; HIST1H3A; histone H3.1

Swiss Prot

P68431

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human Histone H3 (acetyl K56)

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Acetylated

Molecular Weight

15kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Histone H3 (acetyl K56) Antibody detects endogenous levels of total Histone H3 (acetyl K56)

Applications Notes

Western blot analysis of Histone H3 (acetyl K56) expression in C6 cell lysate, treated with TSA.

Host or Source

Rabbit

Available Sizes

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