C9 Rabbit monoclonal antibody
Product Specifications
Background
C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71kDa. Normal plasma concentration is 60mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 molecules. This is the basis of the hydrophilic, protein-walled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Complement component C9; Comple Complement component C9bment component C9a
Swiss Prot
P02748
Reactivity
Human
Immunogen
A synthesized peptide derived from human C9
Conjugation
Unconjugated
Applications
WB IHC IP
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
C9 Antibody detects endogenous levels of total C9
Applications Notes
Western blot (WB) analysis of C9 Rabbit monoclonal antibody at 1:500 dilution Lane1:human blood
Host or Source
Rabbit
Available Sizes
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