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Phospho-Histone H3 (T3) Rabbit monoclonal antibody

Product Specifications

Background

H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

H3 histone family, member A; H3/A; H31; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1H3A

Swiss Prot

P84243

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-Histone H3 (T3)

Conjugation

Unconjugated

Applications

WB IHC ICC/IF FC

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC 1:50~1:200 FC 1:50

Purity

Affinity-chromatography

Modification

Phosphorylated

Molecular Weight

16kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-Histone H3 (T3) Antibody detects endogenous levels of total Phospho-Histone H3 (T3)

Applications Notes

Western blot analysis of Phospho-Histone H3 (Thr3) in HeLa cell lysates treated with FBS + Calyculin A.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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