SATB2 Rabbit monoclonal antibody

Product Specifications

Background

Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

GLSS; SATB family member 2; SATB homeobox 2; SATB2; Special AT rich sequence binding protein 2

Swiss Prot

Q9UPW6

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human SATB2

Conjugation

Unconjugated

Applications

WB IHC ICC/IF

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

~ 85 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

SATB2 Antibody detects endogenous levels of total SATB2

Applications Notes

Western blot (WB) analysis of SATB2 Rabbit monoclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate (30ug) Lane2:HEK293T whole cell lysate (30ug)