SATB2 Rabbit monoclonal antibody
Product Specifications
Background
Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
GLSS; SATB family member 2; SATB homeobox 2; SATB2; Special AT rich sequence binding protein 2
Swiss Prot
Q9UPW6
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human SATB2
Conjugation
Unconjugated
Applications
WB IHC ICC/IF
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
~ 85 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SATB2 Antibody detects endogenous levels of total SATB2
Applications Notes
Western blot (WB) analysis of SATB2 Rabbit monoclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate (30ug) Lane2:HEK293T whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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