RNF20 Rabbit monoclonal antibody
Product Specifications
Background
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) . H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively) . It thereby plays a central role inb histone code and gene regulation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
RING finger protein 20; BRE1A; RNF20
Swiss Prot
Q5VTR2
Reactivity
Human Mouse
Immunogen
A synthesized peptide derived from human RNF20
Conjugation
Unconjugated
Applications
WB ICC/IF IP FC
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
114kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RNF20 Antibody detects endogenous levels of total RNF20
Applications Notes
Western blot analysis of RNF20 in (1) MCF7 cell lysate; (2) HeLa cell lysate.
Host or Source
Rabbit
Available Sizes
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