FAP polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
FAP; DPPIV; FAPA; FAPalpha; SIMP
Swiss Prot
Q12884
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FAP.
Conjugation
Unconjugated
Applications
WB IHC IF/ICC
Dilution
WB: 1:500-1:1000 IHC: 1:100-1:200 IF/ICC: 1:100-1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FAP polyclonal antibody detects endogenous levels of FAP protein.
Applications Notes
Western blot analysis of FAP alpha expression in PC3 (A), H9C2 (B), CT26 (C), Hela (D) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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