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APOA1 polyclonal antibody

Product Specifications

Background

The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA) . The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Apo AI; Apo-AI; ApoA I; ApoA-I; APOA1; APOA1/APOC3 fusion gene; APOA1; Apolipoprotein A I precursor; Apolipoprotein A-I (1-242) ; Apolipoprotein A1; Apolipoprotein AI; Apolipoprotein of high density lipoprotein; ApolipoproteinAI; Brp14; Ltw1; Lvtw1; MGC117399; Sep1; Sep2

Swiss Prot

P02647

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human APOA1.

Conjugation

Unconjugated

Related Pathways

Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease

Applications

WB

Dilution

WB: 1:500~1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 24 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

APOA1 polyclonal antibody detects endogenous levels of APOA1 protein.

Applications Notes

Western blot (WB) analysis of APOA1 pAb at 1:1000 dilution Lane1:PC12 whole cell lysate (30ug) Lane2:CT-26 whole cell lysate (30ug) Lane3:The Liver tissue lysate of Mouse (30ug) Lane4:HCT116 whole cell lysate (30ug) Lane5:HepG2 whole cell lysate (30ug)

Host or Source

Rabbit

Available Sizes

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