APOA1 polyclonal antibody
Product Specifications
Background
The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA) . The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Apo AI; Apo-AI; ApoA I; ApoA-I; APOA1; APOA1/APOC3 fusion gene; APOA1; Apolipoprotein A I precursor; Apolipoprotein A-I (1-242) ; Apolipoprotein A1; Apolipoprotein AI; Apolipoprotein of high density lipoprotein; ApolipoproteinAI; Brp14; Ltw1; Lvtw1; MGC117399; Sep1; Sep2
Swiss Prot
P02647
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human APOA1.
Conjugation
Unconjugated
Related Pathways
Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Applications
WB
Dilution
WB: 1:500~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 24 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
APOA1 polyclonal antibody detects endogenous levels of APOA1 protein.
Applications Notes
Western blot (WB) analysis of APOA1 pAb at 1:1000 dilution Lane1:PC12 whole cell lysate (30ug) Lane2:CT-26 whole cell lysate (30ug) Lane3:The Liver tissue lysate of Mouse (30ug) Lane4:HCT116 whole cell lysate (30ug) Lane5:HepG2 whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
Curated Selection
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