IL-4R/CD124 polyclonal antibody
Product Specifications
Background
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Soluble interleukin-4 receptor subunit alpha; CD124; IL4R; IL4RA
Swiss Prot
P24394
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human IL-4R/CD124.
Conjugation
Unconjugated
Applications
IF
Dilution
IF: 1:100~1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IL-4R/CD124 polyclonal antibody detects endogenous levels of IL-4R/CD124 protein.
Applications Notes
Immunofluorescence analysis of RAW264.7 cells using IL-4R/CD124 pAb at dilution of 1:200 (40x lens) .
Host or Source
Rabbit
Available Sizes
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