Hexokinase II polyclonal antibody

Product Specifications

Background

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

HK2; HKII; HXK2; hexokinase-2

Swiss Prot

P52789

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein corresponding to a sequence within amino acids 1-120 of human Hexokinase II (NP_000180.2) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:500 - 1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .