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Aconitase 2 (ACO2) polyclonal antibody

Product Specifications

Background

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

ACO2; ACONM; HEL-S-284; ICRD; OCA8; OPA9

Swiss Prot

Q99798

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length protein of human Aconitase 2.

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 95 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Aconitase 2 (ACO2) polyclonal antibody detects endogenous levels of Aconitase 2 protein.

Applications Notes

Western blot analysis of Aconitase 2 expression in Hela (A) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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