SDHA polyclonal antibody
Product Specifications
Background
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
SDHA; CMD1GG; FP; PGL5; SDH1; SDH2; SDHF
Swiss Prot
P31040
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length protein of human SDHA.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SDHA polyclonal antibody detects endogenous levels of SDHA protein.
Applications Notes
Western blot analysis of SDHA expression in HepG2 (A), MCF7 (B), mouse liver (C), mouse stomach (D) whole cell lysates.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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