Phospho-IKKα-S180 polyclonal antibody
Product Specifications
Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CHUK; IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16; IKK alpha
Swiss Prot
O15111
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphorylated peptide around S180 of human IKKα (NP_001269.3) .
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB:1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylated
Molecular Weight
~ 85 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-IKKα-S180 polyclonal antibody detects endogenous levels of IKKα protein only when phosphorylated at Ser180.
Applications Notes
Western blot analysis of Phospho-IKKα-S180 expression in mouse testis (A), rat testis (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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