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Butyrylcholinesterase polyclonal antibody

Product Specifications

Background

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

BCHE; CHE1; CHE2; E1

Swiss Prot

P06276

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human Butyrylcholinesterase (NP_000046.1) .

Conjugation

Unconjugated

Applications

WB

Dilution

WB,1:500 - 1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 68 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Butyrylcholinesterase polyclonal antibody detects endogenous levels of Butyrylcholinesterase protein.

Applications Notes

Western blot analysis of Butyrylcholinesterase expression in HEK293T (A), SW620 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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