Butyrylcholinesterase polyclonal antibody
Product Specifications
Background
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
BCHE; CHE1; CHE2; E1
Swiss Prot
P06276
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human Butyrylcholinesterase (NP_000046.1) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 68 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Butyrylcholinesterase polyclonal antibody detects endogenous levels of Butyrylcholinesterase protein.
Applications Notes
Western blot analysis of Butyrylcholinesterase expression in HEK293T (A), SW620 (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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