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Beta 2 Microglobulin polyclonal antibody

Product Specifications

Background

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

B2M; IMD43

Swiss Prot

P61769

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human beta 2 Microglobulin (NP_004039.1) .

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 12 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Beta 2 Microglobulin polyclonal antibody detects endogenous levels of beta 2 Microglobulin protein.

Applications Notes

Western blot analysis of Beta 2 Microglobulin expression in Jurkat (A), COS7 (B), K562 (C), mouse lung (D), mouse liver (E) whole cell lysates.

Host or Source

Rabbit

Available Sizes

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