Beta 2 Microglobulin polyclonal antibody
Product Specifications
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
B2M; IMD43
Swiss Prot
P61769
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human beta 2 Microglobulin (NP_004039.1) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 12 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Beta 2 Microglobulin polyclonal antibody detects endogenous levels of beta 2 Microglobulin protein.
Applications Notes
Western blot analysis of Beta 2 Microglobulin expression in Jurkat (A), COS7 (B), K562 (C), mouse lung (D), mouse liver (E) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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