USP22 polyclonal antibody
Product Specifications
Background
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
USP22; USP3L
Swiss Prot
Q9UPT9
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human USP22 (NP_056091.1) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
USP22 Polyclonal Antibody detects endogenous levels of USP22 protein.
Applications Notes
Western blot analysis of USP22 expression in HeLa (A), mouse brain (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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