GSDMD (Full Length+N terminal) polyclonal antibody
Product Specifications
Background
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
DF5L; DFNA5L; FKSG10; GSDMDC1; GSDMD
Swiss Prot
P57764
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 346-484 of human GSDMD (NP_079012.3) .
Conjugation
Unconjugated
Applications
WB IF/ICC
Dilution
WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 53 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GSDMD polyclonal antibody detects endogenous levels of GSDMD protein.
Applications Notes
Western blot analysis of various lysates using GSDMD pAb at 1:1000 dilution.
Host or Source
Rabbit
Available Sizes
Curated Selection
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