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GSDMD (Full Length+N terminal) polyclonal antibody

Product Specifications

Background

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

DF5L; DFNA5L; FKSG10; GSDMDC1; GSDMD

Swiss Prot

P57764

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 346-484 of human GSDMD (NP_079012.3) .

Conjugation

Unconjugated

Applications

WB IF/ICC

Dilution

WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 53 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

GSDMD polyclonal antibody detects endogenous levels of GSDMD protein.

Applications Notes

Western blot analysis of various lysates using GSDMD pAb at 1:1000 dilution.

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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