EAR2 polyclonal antibody

Product Specifications

Background

EAR2 (v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2) protein binds a cis enhancer element (TGACCT motif) upstream of the reningene and represses renin gene transcription. EAR2 also contributes togonadotropin-dependent derepression of LHR promoter activity in granulosacells. EAR2 mRNA is abundant in the liver, and EAR2 protein localizes to thenucleus of As4.1 cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Product Name Alternative

Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2; NR2F6; EAR2; ERBAL2

Swiss Prot

P10588

Reactivity

Human, Pig

Immunogen

Synthetic peptide, corresponding to Human EAR2.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:2000~1:5000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 51 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

EAR2 polyclonal antibody detects endogenous levels of EAR2 protein.

Applications Notes

Western blot (WB) analysis of EAR2 polyclonal antibody at 1:2000 dilution Lane1:The Lung tissue lysate of Pig (40ug) Lane2:The Kidney tissue lysate of Pig (40ug)