EAR2 polyclonal antibody
Product Specifications
Background
EAR2 (v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2) protein binds a cis enhancer element (TGACCT motif) upstream of the reningene and represses renin gene transcription. EAR2 also contributes togonadotropin-dependent derepression of LHR promoter activity in granulosacells. EAR2 mRNA is abundant in the liver, and EAR2 protein localizes to thenucleus of As4.1 cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2; NR2F6; EAR2; ERBAL2
Swiss Prot
P10588
Reactivity
Human, Pig
Immunogen
Synthetic peptide, corresponding to Human EAR2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:2000~1:5000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 51 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
EAR2 polyclonal antibody detects endogenous levels of EAR2 protein.
Applications Notes
Western blot (WB) analysis of EAR2 polyclonal antibody at 1:2000 dilution Lane1:The Lung tissue lysate of Pig (40ug) Lane2:The Kidney tissue lysate of Pig (40ug)
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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