Rabenosyn-5 (H178) polyclonal antibody
Product Specifications
Background
Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Rabenosyn-5; 110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN; Zinc finger FYVE domain-containing protein 20; RBSN; RBSN
Swiss Prot
Q9H1K0
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 118-238 of Human Rabenosyn-5
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 88 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Rabenosyn-5 (H178) polyclonal antibody endogenous levels of Rabenosyn-5 protein.
Applications Notes
Western blot (WB) analysis of Rabenosyn-5 (H178) polyclonal antibody at 1:500 dilution Lane1:Myla2059 whole cell lysate (40ug) Lane2:HUT78 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:Jurkat whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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