Cathepsin D (HC) polyclonal antibody
Product Specifications
Background
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cathepsin D; Cathepsin D heavy chain; CTSD; CPSD
Swiss Prot
P07339
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human Cathepsin D (Heavy chain) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 28, 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Cathepsin D (HC) polyclonal antibody detects endogenous levels of Cathepsin D heavy chain (27 kDa) Protein.
Applications Notes
Western blot (WB) analysis of Cathepsin D (HC) pAb at 1:500 dilution Lane1:L02 whole cell lysate (40ug) Lane2:H1792 whole cell lysate (40ug) Lane3:The Embryo tissue lysate of Mouse (20ug) Lane4:The Lung tissue lysate of Rat (40ug)
Host or Source
Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![IL-4 Antibody [11B11]](https://cdn.genprice.uk/genprice/genprice4.png)