CTDSP1 polyclonal antibody

Product Specifications

Background

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Nuclear LIM interactor-interacting factor 3; NLI-IF; NLI-interacting factor 3; Small C-terminal domain phosphatase 1; SCP1; Small CTD phosphatase 1; CTDSP1; NIF3, NLIIF, SCP1

Swiss Prot

Q9GZU7

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding Human CTDSP1.

Conjugation

Unconjugated

Applications

WB IP

Dilution

WB: 1:500~1:1000 IP: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 29 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CTDSP1 polyclonal antibody detects endogenous levels of CTDSP1protein.

Applications Notes

Western blot (WB) analysis of CTDSP1 polyclonal antibody at 1:500 dilution Lane1:NIH-3T3 whole cell lysate (40ug) Lane2:PMVEC whole cell lysate (40ug) Lane3:H1792 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug)