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MRPL51 polyclonal antibody

Product Specifications

Background

Mammalian mitochondrial ribosomes (mitoribosomes) are responsible for protein synthesis within the mitochondrion. The mitoribosomes are composed of a 4:1 ratio of protein to RNA, with the proteins forming two subunits, the 28S subunit and the 39S subunit. Across species, the proteins that make up the mitoribosome subunits vary greatly in sequence, preventing easy recognition by sequence homology. MRP-L51 (mitochondrial ribosomal protein L51), also known as CDA09, MRP64, bMRP64 or HSPC241, is a 128 amino acid mitochondrial ribosomal protein. MRP-L51 is a component of the mitochondrial ribosome large subunit (39S) which consists of a 16S rRNA and about 50 distinct proteins

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

39S ribosomal protein L51, mitochondrial; L51mt; MRP-L51; bMRP-64; bMRP64

Swiss Prot

Q4U2R6

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 59-103 of Human MRPL51.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 15 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MRPL51 polyclonal antibody detects endogenous levels of MRPL51 protein.

Applications Notes

Western blot (WB) analysis of MRPL51 pAb at 1:3000 dilution Lane1:AML-12 whole cell lysate (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:Beas-2B whole cell lysate (40ug) Lane4:L02 whole cell lysate (40ug)

Host or Source

Rabbit

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