Cox-17 (N8) polyclonal antibody
Product Specifications
Background
Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cytochrome c oxidase copper chaperone; COX17
Swiss Prot
Q14061
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to the N-terminal of Human Cox-17.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 15 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
COX17 (N8) polyclonal antibody detects endogenous levels of COX17 protein.
Applications Notes
Western blot (WB) analysis of Cox-17 (N8) pAb at 1:500 dilution Lane1:PC3 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:Panc1 whole cell lysate (40ug) Lane4:H9C2 whole cell lysate (40ug) Lane5:AML-12 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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