LGR5/GPR49 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
LGR5; FEX; GPR49; GPR67; GRP49; HG38
Swiss Prot
O75473
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human LGR5/GPR49 (NP_003658.1) .
Conjugation
Unconjugated
Applications
WB, IP
Dilution
WB,1:500 - 1:2000|IP,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
100KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LGR5/GPR49 polyclonal antibody detects endogenous levels of LGR5/GPR49 protein.
Applications Notes
Western blot analysis of LGR5/GPR49 expression in A431 (A), mouse brain (B), rat skeletal muscle (C) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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