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Sox-8/9/17/18 (K148) polyclonal antibody

Product Specifications

Background

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Transcription factor SOX-8; SOX8; Transcription factor SOX-9; SOX9; Transcription factor SOX-17; SOX17; Transcription factor SOX-18; SOX18

Swiss Prot

P57073/P48436/Q9H6I2/P35713

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide, corresponding to Human Sox-8/9/17/18.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 50-70 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Sox-8/9/17/18 (K148) polyclonal antibody detects endogenous levels of Sox-8/9/17/18 protein.

Applications Notes

Western blot (WB) analysis of Sox-8/9/17/18 (K148) polyclonal antibody at 1:500 dilution Lane1:The Brain tissue lysate of Rat Lane2:PC12 whole cell lysate (30ug) Lane3:CT-26 whole cell lysate (30ug) Lane4:U-87MG whole cell lysate (30ug) Lane5:SK-OVCAR3 whole cell lysate (30ug) Lane6:Panc1 whole cell lysate (30ug)

Host or Source

Rabbit

Available Sizes

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