PIP5K1A polyclonal antibody
Product Specifications
Background
Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Acts as an activator of TUT1 adenylyltransferase activity in nuclear speckles, thereby regulating mRNA polyadenylation of a select set of mRNAs. Contributes to the activation of PLD2.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PIP5K1-alpha; PIP5KIalpha; PIP5KIα
Swiss Prot
Q99755
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 231-500 of human PIP5K1A (NP_001129109.1) .
Conjugation
Unconjugated
Applications
WB IHC-P
Dilution
WB 1:500 - 1:2000 IHC-P 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 63 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PIP5K1A polyclonal antibody detects endogenous levels of PIP5K1A protein.
Applications Notes
Western blot analysis of extracts of HeLa cells, using PIP5K1A antibody at 1:1000 dilution.
Host or Source
Rabbit
Available Sizes
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