NAE1 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NAE1; A-116A10.1; APPBP1; HPP1; ula-1
Swiss Prot
Q13564
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NAE1 (NP_003896.1) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
60KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NAE1 polyclonal antibody detects endogenous levels of NAE1 protein.
Applications Notes
Western blot analysis of APPBP1 expression in SHSY5Y (A), SW620 (B), NIH3T3 (C), mouse lung (D), rat brain (E) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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