CD212 polyclonal antibody

Product Specifications

Background

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta component; CD_antigen: CD212; IL12RB1; IL12R; IL12RB

Swiss Prot

P42701

Reactivity

Human

Immunogen

Recombinant protein of human CD212.

Conjugation

Unconjugated

Applications

WB IF

Dilution

WB: 1:1000~1:2000 IF: 1:100~1:500

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CD212 polyclonal antibody detects endogenous levels of CD212 protein.

Applications Notes

Western blot (WB) analysis of CD212 polyclonal antibody at 1:1000 dilution Lane1:MCF-7 whole cell lysate (30ug) Lane2:EC9706 whole cell lysate (30ug) Lane3:K562 whole cell lysate (30ug)