CD141 polyclonal antibody
Product Specifications
Background
CD141/Thrombomodulin (TM, THBD, BDCA-3) is an integral membrane protein expressed on the surface of endothelial cells. Acting as a cofactor with Thrombin, CD141/Thrombomodulin activates and initiates the Protein C anticoagulant pathway. CD141/Thrombomodulin is expressed by a small subset of human CD11c+ myeloid dendritic cells. These CD141+XCR1+ dendritic cells cross-present antigens to naïve CD8+ T cells, priming them to become activated cytotoxic CD8+ T cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM
Swiss Prot
P07204
Reactivity
Human
Immunogen
Recombinant protein of human CD141.
Conjugation
Unconjugated
Applications
IF
Dilution
IF: 1:100~1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD141 polyclonal antibody detects endogenous levels of CD141 protein.
Host or Source
Rabbit
Available Sizes
Curated Selection
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